Poly-L-Lactic Acid is a biocompatible and biodegradable synthetic polymer. It is commonly used in medical and aesthetic applications due to its ability to stimulate collagen production when injected into the skin. PLLA has been approved by regulatory authorities for certain cosmetic uses, particularly in the treatment of facial volume loss and wrinkles.
How Polylactic Acid Stimulates Collagen Production:
Collagen Stimulation: When injected into the skin, polylactic acid microparticles trigger a foreign body response. The body perceives these microparticles as foreign objects and reacts by activating fibroblasts (cells responsible for collagen production) in the treated area.
Collagen Synthesis: The stimulated fibroblasts start producing new collagen around the microparticles. Over time, this newly synthesized collagen helps to increase the skin's thickness and firmness.
Technique: PLLA is typically injected into the deep dermis or subcutaneous tissue using cannula.
Anesthesia: Topical or local anesthesia may be used but not required
Recovery Time: Some individuals may experience mild swelling, bruising, or redness at the injection sites, which typically resolves within a few days. PLLA injections generally have minimal downtime. Patients can usually resume normal activities immediately after the procedure.
Pain Level: Discomfort during PLLA injections is usually minimal. The use of topical anesthesia helps manage any potential pain.
Long-Lasting Effects: The effects of polylactic acid fillers can last longer than some other dermal fillers. While individual results may vary, they can typically last for a year or more.
Improvement in Skin Quality: Beyond adding volume, polylactic acid injections can improve overall skin quality by enhancing thickness and elasticity, reducing the appearance of fine lines and wrinkles.
Biocompatibility: PLA is biocompatible and biodegradable, meaning it is generally well-tolerated by the body and breaks down over time into harmless byproducts.
Duration:The effects can last 1-2 years but depends on the skin type, age and skin care including sun protection.